This formula is an Optimal methylation formula with activating co-factor created to support the methylation pathway and provide adequate Folinic Acid and methyl folate (5-MTHF).
Dual Folate Enhancer is designed to provide the activating co-factors to deliver the additional tetrahydrofolate to support issues associated with methylation deficiencies.. Most often poor methylators will need additional methyl folate.
The addition of Niacinamide helps support the mitochondria and supports as a cofactor for the delivery of the other ingredients in Methyl Folate Plus.
The typical indications for this product include but are not limited to:
* Presence of Folate Receptor Autoantibodies
*Homozygous (2 copies) MTHFR polymorphism
*Development (ages 8-20)
*Slow recovery from major neurological injuries
*Moderate to severe autism spectrum issues
*Poor recovery from traumatic injury
What Is PEA?
Palmitoylethanolamide (PEA) is a bio-identical fatty acid amide that Is normally synthesized by healthy tissue In the human body in response to inflammation. PEA is made by various plants and animals and is present throughout the animal kingdom. PEA can be found in many different tissuesincluding glia, neurons, retina, white blood cells, mast cells and adipocytes. Supplementing with PEA has been sclentlffcally shown to naturally assist in the reduction of inflammation and to have neuro-protective and possibly pain control effects. This natural anti-inflammatory supports the nervous system and abnormal immune responses.*
Palmitoylethanolamide (PEA) – backed by more than 300+ medical studies, has been shown to be or assist with:
Mast cells are a type of immune system cell that responds to chemical signals from tissue injury. When mast cells “degranulate,” they release a payload of inflammatory cytokines, NGF, histamines, and other molecules in the surrounding tissue. These chemicals attract white blood cells and activate their immune response against pathogens. Mast cells also activate nociceptors (pain receptors) with the chemicals they secrete. How does it work?Palmitoylethanolamide is thought to act primarily on the Peroxisome Proliferator Activated Receptor Alpha (PPAR-α), a receptor in the cell nucleus. It also has affinity for the cannabinoid-like G-coupled receptors GPR55 and GPR119, although it has no affinity for the classical cannabinoid receptors CB1 and CB2. This is why it is sometimes referred to as a non-psychoactive “indirect endocannabinoid.”
It does not block pain signals the way opioids and other analgestics do. Instead it works upstream by supporting the healthy function of glial cells and mast cells.*
Cellular Enhancer is a combination of well-studied nutritional ingredients that are known to enhance multiple biologic pathways within the cell. This unique combination was chosen to enhance 3 important pathways of intracellular detoxification. The 3 pathways include: 1) Activating the leucine zipper protein in the NRF2 genetic pathway to enhance glutathione production2) Down regulating the mTOR system of the cell and activate autophagy (intracellular cleansing of by-products)3) Providing maximum assistance with antioxidant neutralization within the cellEach of these important activities has been shown to protect cells from oxidative stressors and damage while combating the aging process.*
What is D-Chiro-Inositol?D-Chiro Inositol (DCI) is a sugar alcohol complex that is naturally produced by the body. It is a member of the B vitamin family and plays an essential role in the pathways of mitochondria and energy in the cells to generate energy from sugar. When you eat food, sugar is extracted and absorbed into the blood. Insulin is released by the pancreas in response to the sugar, telling the cells in your body to either burn the sugar for energy or store it as fat for later. As sugar levels go down, so do insulin levels. DCI acts as a secondary messenger in the insulin signaling process and can help reduce insulin resistance.*
9 ingredients to assist in the support and function of the mitochondria.
Pyrroloquinoline Quinone(PQQ) and NADH(B3) are two major ingredients which form this powerful supplement. With the combination of these 9 ingredients, selected by our advising physicians, ensures that these key ingredients stimulate proper mitochondrial function and guard against mitochondrial degeneration.