What Is PEA?
Palmitoylethanolamide (PEA) is a bio-identical fatty acid amide that Is normally synthesized by healthy tissue In the human body in response to inflammation. PEA is made by various plants and animals and is present throughout the animal kingdom. PEA can be found in many different tissuesincluding glia, neurons, retina, white blood cells, mast cells and adipocytes. Supplementing with PEA has been sclentlffcally shown to naturally assist in the reduction of inflammation and to have neuro-protective and possibly pain control effects. This natural anti-inflammatory supports the nervous system and abnormal immune responses.*
Palmitoylethanolamide (PEA) – backed by more than 300+ medical studies, has been shown to be or assist with:
Mast cells are a type of immune system cell that responds to chemical signals from tissue injury. When mast cells “degranulate,” they release a payload of inflammatory cytokines, NGF, histamines, and other molecules in the surrounding tissue. These chemicals attract white blood cells and activate their immune response against pathogens. Mast cells also activate nociceptors (pain receptors) with the chemicals they secrete. How does it work?Palmitoylethanolamide is thought to act primarily on the Peroxisome Proliferator Activated Receptor Alpha (PPAR-α), a receptor in the cell nucleus. It also has affinity for the cannabinoid-like G-coupled receptors GPR55 and GPR119, although it has no affinity for the classical cannabinoid receptors CB1 and CB2. This is why it is sometimes referred to as a non-psychoactive “indirect endocannabinoid.”
It does not block pain signals the way opioids and other analgestics do. Instead it works upstream by supporting the healthy function of glial cells and mast cells.*
9 ingredients to assist in the support and function of the mitochondria.
Pyrroloquinoline Quinone(PQQ) and NADH(B3) are two major ingredients which form this powerful supplement. With the combination of these 9 ingredients, selected by our advising physicians, ensures that these key ingredients stimulate proper mitochondrial function and guard against mitochondrial degeneration.